Does Lysol Kill Spiders? (What Disinfectant Kills Spiders?)

Do you see spiders hanging over your ceiling and or door frame and you’re wondering if your can of disinfectant Lysol spray can kill them? Do you have a spider situation at home or in your office and you want to confirm if your go-to household cleaning Lysol spray can do the job? 

Here’s an article to discuss whether Lysol can kill spiders hanging about in your home or office. Read on to discover if Lysol can kill spiders.

There are a few ways to kill spiders in your home or office and spraying Lysol on them is one way to kill them. However, it would take about 1/2 a can of Lysol disinfectant spray to kill the spider hanging on your door frame or ceiling. 

Instead, there are faster and more effective ways to kill and repel spiders from your home or office, by purchasing a spider insecticide spray at the local supermarket which would be recommended in the article, or simply using bleach. 

The article will discuss how to effectively use the Lysol disinfectant spray to kill spiders, (although this process is slower and requires much use of the spray). While recommending products that are effective in killing and repealing spiders in your home. 

Does Lysol Kill Pinworm Eggs
Image: @chara_stagram_ via Twenty20

Does Lysol Effectively Kill Spiders?

Lysol disinfectant spray is an effective way to both effectively clean your home or office spaces, and kill about 99.9% of germs or bugs leeching about in your environment. 

That is why it is no surprise when we wonder or experiment if Lysol can effectively kill or repel spiders and spider webs hanging around in your home or office spaces.

Yes, spraying Lysol disinfectant can kill spiders, it would, however, take a significant amount of time and Lysol spray to kill said the spider. Also, the plus side is that Lysol acts as a good repellant for spider nests, hence you can spray Lysol around your home or near suspected spider nests area in your living space. 

It has been tested that it takes about 1/2 a can of Lysol disinfectant spray to kill a spider hanging around in your home or office. Also, for Lysol to work most effectively it should be sprayed at a distance of about 2 meters, meaning you would have to move closer to said spider.

Although Lysol has a pleasant smell for a disinfectant spray, it is said to linger for some time. Thus, imagine having to spray such an amount of Lysol into an entryway or sparsely ventilated area, this may make you slightly heady. 

lysol cleaner

What Disinfectant Kills Spiders?

Generally, effectively killing and repelling spiders and their webs around your living area is no easy feat, especially when you cannot stand squashing or killing them with anything laying around.

Foremost, the acidity content inside bleach gives it the ability to kill household pests, including spiders. However, it is not a registered insecticide because of its harmful side effects, and caution should be exercised when used to kill spiders or pests. 

Hence, we have rounded up and suggested the best ranked and price-friendly spider-killing insecticide (s), that will permanently kill and repel spiders and their webs from your home and office. 

1. Ortho Home Defense Insect Killer for indoor and perimeter

Ortho Home Defense Insect Killer for Indoor & Perimeter2: With Comfort Wand, Kills Ants, Cockroaches, Spiders, Fleas & Ticks, Odor Free, 1.1 gal.

This is odor free, free from stains, pleasant smelling,  and kills best the listed insects above. It is a best-seller-recommended insect-killing insecticide, that works well in killing and repelling spiders. 

This product’s best features are its easy applicator wand that comes with the product, leaves no residue or stain when sprayed, effectively kills spiders and bugs, and has pleasant reviews on the website. 

2. Ortho Home Defense Max Ant, Roach, and Spider Spray

Ortho Home Defense Max Ant, Roach and Spider1 - Indoor Insect Spray, Kills Ants, Beetles, Cockroaches and Spiders (as Listed), No Fumes, Spray at Any Angle, 14 oz.

Here is a highly recommended insect-killing spray that works best for indoor bugs including spiders. They are long-lasting, well angled for precise use, pairs well with indoor surfaces around your home, are budget-friendly, kills spiders fast, and will not leave behind any sticky residue. This is a good pick, for persons sensitive to smell. 

3. Demon Max Insecticide Pint

Demon Max Insecticide Pint 25.3% Cypermethrin

This is Amazon’s choice, budget, and customer-friendly insect-killing insecticide. This product is popular because it has a long shelf life, it remains effective for many years, is easy to use, has great reviews on the Amazon website, and is high quality for repelling spiders. 

4. TERRO T3400B indoor and outdoor home insect and spider killer

TERRO T3400B Indoor And Outdoor Home Insect Killer, 1 Gallon – Kills Ants, Cockroaches, Spiders, Fleas and Ticks

This is a great choice because it can be used both indoors and outdoors, great for killing spiders, and centipedes. ants and roaches. It has a great shelf life, easy to use, and is odorless. 

5. Palmandpond Ultrasonic Pest Repellant

Ultrasonic Pest Repeller 6 Packs, Electronic Plug in Sonic Repellent pest Control for Bugs Insects Roaches Mice Spiders Rodents Mosquitoes

This is a best-seller insect-killing product due to its intelligent frequency conversion technology and ultrasonic waves qualities it helps kill, repel and protect your home from bugs, insects, and spiders. It is energy saving, has humanized designs, and is healthy to use around kids and pets too. 

How To Spider-Proof Your Home

The best way to solve a spider situation in your home or office space is by making sure these spaces are spider-proof and unwelcoming to spiders or them layering their nests around your living area. 

Here are some highlighted tips on how to spider-proof your home;

1. Start with making sure you have successfully removed all lingering spider wends or nests lurking or hanging on your doorframes, ceilings, windows, or around the home. 

2. Ensure to disinfect and clean your home with either bleach, disinfectant liquids, or vinegar

3. Introduce smells that you know spiders hate like essential oils (like eucalyptus oil, peppermint oil, or tea tree oil) on them, citrus, lemon, vanilla, disinfectant sprays, etc. 

4. Always ensure to maintain a clean home and check that there is no dust or dirt stuck to hidden or dark corners of your rooms or homes. 

5. Apply spider-killing insecticides or sprays to any spider, seen still lurking around. 

Now you are good to go and free from spider and their webs from invading your home and living area. 

Frequently Asked Questions

What household products kill spiders?

Household products like vinegar, baking soda, essential oils (such as eucalyptus oil, peppermint oil, tea tree oil, etc.), turmeric, and citrus are popular for killing and repelling spiders lurking around your home. 

What kills spiders instantly?

To instantly kill a spider (s), spray them with either a chemical-based commercial formula, or a homemade mixture of equal parts white vinegar and water, or you could easily squash them. 

Can cleaning spray kill spiders?

It is of popular opinion that Windex can be very effective in killing spiders, and large numbers of ants or pests. Also, using Windex around your home is safe for humans. 


We all tend to scream and get irritated when spotting a spider or its webs in any part of our home. The first thought would be to squash them, however, some people cannot do this, and squashing them doesn’t offer a long-lasting solution. 

We need to both effectively kill and repel spiders and their webs from invading our homes and spraying Lysol disinfectant can help mitigate this problem. The downside is that a significant amount of Lysol has to be sprayed on the said spider and the result is a slower killing process. 

Additionally, this article has highlighted suggested methods that can be used to kill spiders like bleach, spider-killing sprays, spritzing essential oils, etc.

We hope this article was helpful, and now you are aware of several natural remedies for killing spiders lurking or hanging around your home and office area.